Name of the project: Features of numerical methods optimizing dynamic models of biochemical networks

This project is supported by the Baltic-German University Liaison Office through German Academic Exchange Service (DAAD) with funds from the Foreign Office of the Federal Republic of Germany.


Fact sheet

Duration of the project: 01.07. – 10.12.2013.
Aims of the project:
  • further development of interdisciplinary collaboration of specialists with biological and mathematical background in optimisation of biochemical networks,
  • development of collaboration between biologists and software developers,
  • improvement of visibility of interdisciplinary collaboration at international level,
  • assessment of features of optimisation methods of COPASI,
  • development of rational suggestions for the choice of optimisation methods of dynamic models of biochemical networks.
Project partners 1. Latvia University of Agriculture (Latvia)
2. Ruprecht-Karls-University Heidelberg (Germany)
3. Institute of Microbiology and Biotechnology at the University of Latvia (Latvia)
Venue(s) Heidelberg (Germany), Jelgava and Riga (Latvia)
Target group The target group are the participants of interdisciplinary field of systems biology: biologists, biotechnologists and computer scientists. 31 persons are addressed personally via seminars, unknown amount via internet.
Main activities
  • Exchange of experience and agreement about the set-up of numerical experiments.
  • Seminar “Opportunities of optimization of dynamic biochemical networks” in Heidelberg, Germany.
  • Carrying out of optimisation experiments to find out the properties of optimisation methods optimizing biochemical networks. Preparation of scientific publication.
  • Seminar “Algorithms for optimisation of dynamic biochemical networks” for biologists, biotechnologists and information technologists in Riga, Latvia.

Main events

Open seminar in Heidelberg 26.08.2013.

Poster: Heidelberg_poster.doc


Sven Sahle
Egils Stalidzans and Natalja Bulipopa
Katrina Landmane


Open seminar in Riga 17.10. 2013.

Poster: Poster DE, Poster LV, Poster EN


Sven Sahle
Katrina Landmane

Visit of Latvian systems biologists to BIOQUANT at Heidelberg University 21.-28.08.2013.

Egils Stalidzans, Natalja Bulipopa, Jurijs Sulins and Katrina Landmane visted the research centre BIOQUANT at the University of Heidelberg at the end of the summer. Different activities were carried out to coordinate the optimization experiments, exchange the interdisciplinary working skills, draft the idea of a joint scientific publication.

Saturday and Sunday was great for sightseeing discovering the beauty of Heidelberg, Neckar and Rhine valeys.