Group lunch between Christmas and New year

Computational Systems Biology group members travel quite intensively and it is not easy to sit at the same table. We found a moment 27-th December 2019 when Santa is back from ERASMUS+ exchange studies in Helsinki and Darta is in Latvia between semesters studying in University of Gothenburg also within ERASMUS+ program. Also Liva Stalidzane, biology student from University of Nortumbria joined the meeting.

Rhodolive project meets at olive harvesting in Turkey

Mid-term Rhodolive meeting took place 2nd December 2019 in Burhaniye where the olive mill of Laleli company. Project partners could see olive oil production process from collecting olives from trees until degustation of ready oil. The process included also demonstration of process where the olive mill wastewater (OMW) is produced.

Imporatnt result of the project is the bioreactor for OMW fermentation produced during collaboration of project partners from Turkey. The bioreactor enables bigger batch cultivations that are needed by several partners.

Project partners had a joint workshop where the project progress was demonstrated and future activities were coordinated.

International Conference on Systems Biology in Okinawa, Japan

20-th conference of ICSB series took place in Okinawa, Okinawa Institute of Science and Technology 1.-5. November, 2019. Agris Pentjuss and Egils Stalidzans from our group participated in the event. As always, many interesting tutorials and lectures took place on very different topics showing new trends of very versatile systems biology. Quite many people recognized us as organizers of MPA2019 in Riga.

We met also our Estonian colleagues Kaspar Valgepea, Petri-Jaan Lahtvee, Raivo Vilu and Isma Belouah (Lahtvee group). Thus, Baltic countries were well represented!

Trainer in COPASI tutorial!

Traditional COPASI tutorial was organised by COPASI developers as usual at ICSB conferences. In Okinawa it took place 31-st October. For the first time also Computational Systems Biology Group was represented among teachers by Egils Stalidzans. Our part of workshop was “Automated metabolic network optimization workflow” where we presented the total optimisation potential approach (TOP) and SpaceScanner based kinetic model optimisation workflow.

Meeting Rhodolive partners in Kassel


The development of R. glutinis stoichiometric model could benefit from sequencing of our strain of interest and the strain that was result of evolution at Laleli olive oil factory. Our colleagues Egils Stalidzans and Kristaps Berzins met Jonas Peterle and Prof. Dr. Friedrich W. Herberg from University of Kassel. We improved the model with new gene annotations and made our plans for future additions in the model.

Latvians had an opportunity to present their research in a scientific seminar. That was the first international presentation of our colleague Kristaps Berzins.


Seminar No. 14


Seminar No. 14: Selective killing of cancer cells by self-assembly of mixed-charge nanoparticle crystals by Kristiana Kandere-Grzybowska

Our long-term collaborator Kristiana Kandere-Grzybowska Center for Soft and Living Matter, Institute for Basic Science and School of Life Science, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea gave a talk on the progress on their research.

This year she concentrated on the mechanisms of selective killing of cancer cells and how to move closer to the implementation of mixed-charge nanoparticles.

Biomodelling Spring Riga 2019


The second Biomodelling Spring Riga was the 7th training school organised by the COST action CA15120 “Open Multiscale Systems Medicine" (OpenMultiMed). We had four invited speakers.

The main objective was to gather a critical mass of researchers and stakeholders from different disciplines, and coordinate these researchers as a team to define and investigate important S&T challenges in multiscale systems medicine, and to improve existing and develop novel solutions for multiscale systems medicine.

Metabolic Pathway Analysis 2019 brings 120 participants from 25 countries to Riga


120 participants from 25 countries have attended the Metabolic Pathway Analysis 2019 conference in Riga, Latvia on 12 – 16 August. The conference was organized by the Computational Systems Biology Group, Institute of Microbiology and Biotechnology of the University of Latvia, and took place in the Academic centre of the University of Latvia.

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CryZym project progress meeting in the House of Nature


CryZym project partners had one of the meetings 1-st October 2019 to discuss the progress. The project “Crypthecodinium cohnii and Zymomonas mobilis syntrophy for production of omega 3 fatty acid from byproducts of biofuel and sugar industry” has ben started 1-st April 2019 as collaboration our institute with the Institute of Wood Chemistry and JSC "Biotehniskais Centrs".

Regular meetings take place to learn about fermentation parameters of single organism and in co-cultivation. Important issue is also to follow the amount of produced fraction of docosahexaenoic acid (DHA) from omega 3 fatty acid family. JSC Biotehniskais centrs keeps informing about experimental results using alginate beads as well as alginate beads with immobilised Z.mobilis. Institute of Wood Chemistry reports about the progress in separation technology adaptation to collect DHA.

OpenMultiMed COST project meets at Holon Institute of Technology

 Holon Institute of Technology is located in Holon, close to Tel Aviv. The institute has hosted annual Management Committee meeting of OpenMultiMed. Potential publications of COST action have been discussed along with the options of main COST action conference in 2020. The last year of COST action starts in a couple of months.